3biv

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[[Image:3biv.jpg|left|200px]]<br /><applet load="3biv" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:3biv.jpg|left|200px]]
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caption="3biv, resolution 1.8&Aring;" />
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'''Human thrombin-in complex with UB-THR11'''<br />
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{{Structure
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|PDB= 3biv |SIZE=350|CAPTION= <scene name='initialview01'>3biv</scene>, resolution 1.8&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=11U:'>11U</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
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|GENE=
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}}
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'''Human thrombin-in complex with UB-THR11'''
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==About this Structure==
==About this Structure==
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3BIV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=11U:'>11U</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BIV OCA].
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3BIV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BIV OCA].
==Reference==
==Reference==
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Thermodynamic inhibition profile of a cyclopentyl and a cyclohexyl derivative towards thrombin: the same but for different reasons., Gerlach C, Smolinski M, Steuber H, Sotriffer CA, Heine A, Hangauer DG, Klebe G, Angew Chem Int Ed Engl. 2007;46(44):8511-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17902081 17902081]
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Thermodynamic inhibition profile of a cyclopentyl and a cyclohexyl derivative towards thrombin: the same but for different reasons., Gerlach C, Smolinski M, Steuber H, Sotriffer CA, Heine A, Hangauer DG, Klebe G, Angew Chem Int Ed Engl. 2007;46(44):8511-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17902081 17902081]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: blood coagulation]]
[[Category: blood coagulation]]
[[Category: calcium]]
[[Category: calcium]]
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[[Category: cleavage on pair of basic residues]]
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[[Category: cleavage on pair of basic residue]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: disease mutation]]
[[Category: disease mutation]]
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[[Category: zymogen]]
[[Category: zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:06:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:59:23 2008''

Revision as of 16:59, 20 March 2008

Image:3biv.jpg


PDB ID 3biv

Drag the structure with the mouse to rotate
, resolution 1.8Å
Ligands: and
Activity: Thrombin, with EC number 3.4.21.5
Coordinates: save as pdb, mmCIF, xml



Human thrombin-in complex with UB-THR11


About this Structure

3BIV is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Thermodynamic inhibition profile of a cyclopentyl and a cyclohexyl derivative towards thrombin: the same but for different reasons., Gerlach C, Smolinski M, Steuber H, Sotriffer CA, Heine A, Hangauer DG, Klebe G, Angew Chem Int Ed Engl. 2007;46(44):8511-4. PMID:17902081

Page seeded by OCA on Thu Mar 20 18:59:23 2008

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