4om9

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'''Unreleased structure'''
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{{STRUCTURE_4om9| PDB=4om9 | SCENE= }}
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===X-Ray Crystal Structure of the passenger domain of Plasmid encoded toxin, an Autrotansporter Enterotoxin from enteroaggregative Escherichia coli (EAEC)===
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{{ABSTRACT_PUBMED_24530907}}
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The entry 4om9 is ON HOLD until sometime in the future
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==Function==
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[[http://www.uniprot.org/uniprot/PET_ECO44 PET_ECO44]] Serine protease with enterotoxic and cytotoxic activity. Internalization into the host cell is required for the induction of cytopathic effects. However, the serine activity is not necessary for secretion and internalization into the host cell.<ref>PMID:9632580</ref> <ref>PMID:10225873</ref> <ref>PMID:10496914</ref> <ref>PMID:11160002</ref>
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Authors: Meza-Aguilar, J.D., Fromme, P., Torres-Larios, A., Mendoza-Hernandez, G, Hernandez-Chinas, U., Arreguin-Espinoza de los Monteros, R. A., Eslava-Campos, C.A., Fromme, R.
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==About this Structure==
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[[4om9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OM9 OCA].
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Description: X-Ray Crystal Structure of the passenger domain of Plasmid encoded toxin, an Autrotansporter Enterotoxin from enteroaggregative Escherichia coli (EAEC)
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==Reference==
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<ref group="xtra">PMID:024530907</ref><references group="xtra"/><references/>
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[[Category: Eslava-Campos, C A.]]
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[[Category: Fromme, P.]]
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[[Category: Fromme, R.]]
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[[Category: Hernandez-Chinas, U.]]
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[[Category: Mendoza-Hernandez, G.]]
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[[Category: Meza-Aguilar, J D.]]
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[[Category: Monteros, R A.Arreguin-Espinoza de los.]]
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[[Category: Torres-Larios, A.]]
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[[Category: Alpha-fodrin]]
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[[Category: Beta-helix]]
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[[Category: Eaec]]
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[[Category: Hydrolase]]
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[[Category: Peptidase]]

Revision as of 13:41, 12 March 2014

Template:STRUCTURE 4om9

Contents

X-Ray Crystal Structure of the passenger domain of Plasmid encoded toxin, an Autrotansporter Enterotoxin from enteroaggregative Escherichia coli (EAEC)

Template:ABSTRACT PUBMED 24530907

Function

[PET_ECO44] Serine protease with enterotoxic and cytotoxic activity. Internalization into the host cell is required for the induction of cytopathic effects. However, the serine activity is not necessary for secretion and internalization into the host cell.[1] [2] [3] [4]

About this Structure

4om9 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Domingo Meza-Aguilar J, Fromme P, Torres-Larios A, Mendoza-Hernandez G, Hernandez-Chinas U, Arreguin-Espinosa de Los Monteros RA, Eslava Campos CA, Fromme R. X-ray crystal structure of the passenger domain of plasmid encoded toxin(Pet), an autotransporter enterotoxin from enteroaggregative Escherichia coli (EAEC). Biochem Biophys Res Commun. 2014 Feb 12. pii: S0006-291X(14)00268-X. doi:, 10.1016/j.bbrc.2014.02.016. PMID:24530907 doi:http://dx.doi.org/10.1016/j.bbrc.2014.02.016
  1. ↑ Eslava C, Navarro-Garcia F, Czeczulin JR, Henderson IR, Cravioto A, Nataro JP. Pet, an autotransporter enterotoxin from enteroaggregative Escherichia coli. Infect Immun. 1998 Jul;66(7):3155-63. PMID:9632580
  2. ↑ Navarro-Garcia F, Sears C, Eslava C, Cravioto A, Nataro JP. Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coli. Infect Immun. 1999 May;67(5):2184-92. PMID:10225873
  3. ↑ Henderson IR, Hicks S, Navarro-Garcia F, Elias WP, Philips AD, Nataro JP. Involvement of the enteroaggregative Escherichia coli plasmid-encoded toxin in causing human intestinal damage. Infect Immun. 1999 Oct;67(10):5338-44. PMID:10496914
  4. ↑ Navarro-Garcia F, Canizalez-Roman A, Luna J, Sears C, Nataro JP. Plasmid-encoded toxin of enteroaggregative Escherichia coli is internalized by epithelial cells. Infect Immun. 2001 Feb;69(2):1053-60. PMID:11160002 doi:http://dx.doi.org/10.1128/IAI.69.2.1053-1060.2001

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