3c10

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(New page: 200px<br /><applet load="3c10" size="350" color="white" frame="true" align="right" spinBox="true" caption="3c10, resolution 2.00&Aring;" /> '''Crystal structure of...)
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[[Image:3c10.jpg|left|200px]]<br /><applet load="3c10" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:3c10.jpg|left|200px]]
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caption="3c10, resolution 2.00&Aring;" />
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'''Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with Trichostatin A (TSA)'''<br />
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{{Structure
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|PDB= 3c10 |SIZE=350|CAPTION= <scene name='initialview01'>3c10</scene>, resolution 2.00&Aring;
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|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+101'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+102'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+101'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+B+102'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+C+101'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+C+102'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+A+201'>AC7</scene>, <scene name='pdbsite=AC8:K+Binding+Site+For+Residue+A+202'>AC8</scene>, <scene name='pdbsite=AC9:K+Binding+Site+For+Residue+B+201'>AC9</scene>, <scene name='pdbsite=BC1:K+Binding+Site+For+Residue+B+202'>BC1</scene>, <scene name='pdbsite=BC2:K+Binding+Site+For+Residue+C+201'>BC2</scene>, <scene name='pdbsite=BC3:K+Binding+Site+For+Residue+C+202'>BC3</scene>, <scene name='pdbsite=BC4:Tsn+Binding+Site+For+Residue+A+301'>BC4</scene>, <scene name='pdbsite=BC5:Tsn+Binding+Site+For+Residue+B+301'>BC5</scene> and <scene name='pdbsite=BC6:Tsn+Binding+Site+For+Residue+C+301'>BC6</scene>
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=TSN:TRICHOSTATIN A'>TSN</scene>
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|ACTIVITY=
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|GENE= HDAC7A, HDAC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with Trichostatin A (TSA)'''
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==About this Structure==
==About this Structure==
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3C10 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=TSN:'>TSN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2PQP. Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+101'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+102'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+101'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+B+102'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+C+101'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+C+102'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+A+201'>AC7</scene>, <scene name='pdbsite=AC8:K+Binding+Site+For+Residue+A+202'>AC8</scene>, <scene name='pdbsite=AC9:K+Binding+Site+For+Residue+B+201'>AC9</scene>, <scene name='pdbsite=BC1:K+Binding+Site+For+Residue+B+202'>BC1</scene>, <scene name='pdbsite=BC2:K+Binding+Site+For+Residue+C+201'>BC2</scene>, <scene name='pdbsite=BC3:K+Binding+Site+For+Residue+C+202'>BC3</scene>, <scene name='pdbsite=BC4:Tsn+Binding+Site+For+Residue+A+301'>BC4</scene>, <scene name='pdbsite=BC5:Tsn+Binding+Site+For+Residue+B+301'>BC5</scene> and <scene name='pdbsite=BC6:Tsn+Binding+Site+For+Residue+C+301'>BC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C10 OCA].
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3C10 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2PQP. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C10 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: repressor]]
[[Category: repressor]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: transcription]]
[[Category: transcription]]
[[Category: transcription regulation]]
[[Category: transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:02:09 2008''

Revision as of 17:02, 20 March 2008

Image:3c10.jpg


PDB ID 3c10

Drag the structure with the mouse to rotate
, resolution 2.00Å
Sites: , , , , , , , , , , , , , and
Ligands: , and
Gene: HDAC7A, HDAC7 (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with Trichostatin A (TSA)


About this Structure

3C10 is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2PQP. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 19:02:09 2008

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OCA

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