4c3m
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4c3m| PDB=4c3m | SCENE= }} | {{STRUCTURE_4c3m| PDB=4c3m | SCENE= }} | ||
===Structure of wildtype PII from S. elongatus at medium resolution=== | ===Structure of wildtype PII from S. elongatus at medium resolution=== | ||
| + | {{ABSTRACT_PUBMED_24519945}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4c3m]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C3M OCA]. | [[4c3m]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C3M OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024519945</ref><references group="xtra"/><references/> | ||
[[Category: Forchhammer, K.]] | [[Category: Forchhammer, K.]] | ||
[[Category: Zeth, K.]] | [[Category: Zeth, K.]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 15:32, 19 February 2014
Contents |
Structure of wildtype PII from S. elongatus at medium resolution
Template:ABSTRACT PUBMED 24519945
Function
[GLNB_SYNE7] P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is phosphorylated, these events are reversed. In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.
About this Structure
4c3m is a 3 chain structure. Full crystallographic information is available from OCA.
Reference
- Zeth K, Fokina O, Forchhammer K. Structural Basis and Target-Specific Modulation of ADP Sensing by the Synechococcus elongatus PII Signaling Protein. J Biol Chem. 2014 Feb 11. PMID:24519945 doi:http://dx.doi.org/10.1074/jbc.M113.536557
