We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
4l7c
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4l7c]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L7C OCA]. | + | [[4l7c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L7C OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024504667</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024504667</ref><references group="xtra"/><references/> | ||
| + | [[Category: Human]] | ||
[[Category: Albrecht, C.]] | [[Category: Albrecht, C.]] | ||
[[Category: Barker, J J.]] | [[Category: Barker, J J.]] | ||
Revision as of 06:08, 23 April 2014
Structure of keap1 kelch domain with 2-{[(1S)-2-{[(1R,2S)-2-(1H-tetrazol-5-yl)cyclohexyl]carbonyl}-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-1H-isoindole-1,3(2H)-dione
Template:ABSTRACT PUBMED 24504667
About this Structure
4l7c is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Jnoff E, Albrecht C, Barker JJ, Barker O, Beaumont E, Bromidge S, Brookfield F, Brooks M, Bubert C, Ceska T, Corden V, Dawson G, Duclos S, Fryatt T, Genicot C, Jigorel E, Kwong J, Maghames R, Mushi I, Pike R, Sands ZA, Smith MA, Stimson CC, Courade JP. Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex. ChemMedChem. 2014 Feb 6. doi: 10.1002/cmdc.201300525. PMID:24504667 doi:http://dx.doi.org/10.1002/cmdc.201300525
Categories: Human | Albrecht, C. | Barker, J J. | Barker, O. | Beaumont, E. | Bromidge, S. | Brookfield, F. | Brooks, M. | Ceska, T. | Courade, J P. | Crabbe, T. | Duclos, S. | Fryatt, T. | Jigorel, E. | Jnoff, E. | Kwong, J. | Sands, Z. | Smith, M A. | Beta-propeller | Kelch domain | Kelch repeat motif | Nrf2 | Protein-small molecule complex | Stress sensor | Transcription-inhibitor complex
