4l7c

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==About this Structure==
==About this Structure==
-
[[4l7c]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L7C OCA].
+
[[4l7c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L7C OCA].
==Reference==
==Reference==
<ref group="xtra">PMID:024504667</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024504667</ref><references group="xtra"/><references/>
 +
[[Category: Human]]
[[Category: Albrecht, C.]]
[[Category: Albrecht, C.]]
[[Category: Barker, J J.]]
[[Category: Barker, J J.]]

Revision as of 06:08, 23 April 2014

Template:STRUCTURE 4l7c

Structure of keap1 kelch domain with 2-{[(1S)-2-{[(1R,2S)-2-(1H-tetrazol-5-yl)cyclohexyl]carbonyl}-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-1H-isoindole-1,3(2H)-dione

Template:ABSTRACT PUBMED 24504667

About this Structure

4l7c is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Jnoff E, Albrecht C, Barker JJ, Barker O, Beaumont E, Bromidge S, Brookfield F, Brooks M, Bubert C, Ceska T, Corden V, Dawson G, Duclos S, Fryatt T, Genicot C, Jigorel E, Kwong J, Maghames R, Mushi I, Pike R, Sands ZA, Smith MA, Stimson CC, Courade JP. Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex. ChemMedChem. 2014 Feb 6. doi: 10.1002/cmdc.201300525. PMID:24504667 doi:http://dx.doi.org/10.1002/cmdc.201300525

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