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Clp Protease
From Proteopedia
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[[1r6o]], [[1r6q]] - EcCLP N terminal + CLP adaptor protein ClpS | [[1r6o]], [[1r6q]] - EcCLP N terminal + CLP adaptor protein ClpS | ||
| - | ===ATP-dependent CLP - CLPX=== | ||
| - | [[2ds5]], [[2ds6]] – EcCLPX Zn-binding domain<br /> | ||
| - | [[2ds7]] – EcCLPX Zn-binding domain (mutant)<br /> | ||
| - | [[2ds8]] – EcCLPX Zn-binding domain + SSPB-tail peptide<br /> | ||
| - | [[3hte]], [[4i34]], [[4i4l]], [[4i5o]], [[4i63]], [[4i9k]] – EcCLPX<br /> | ||
| - | [[3hws]] – EcCLPX (mutant)<br /> | ||
| - | [[4i81]] – EcCLPX + ATP-γ-S<br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:57, 20 February 2014
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| E. coli Clp protease, 1tyf | |||||||||
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| Activity: | Endopeptidase Clp, with EC number 3.4.21.92 | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Clp protease (CLP) is a serine peptidase which hydrolyzes proteins in the presence of ATP and Mg+2 ion. CLP is found in mitochondria. CLP participates in degradation of misfolded proteins. CLP is a heterodimer containing an ATP-binding regulatory subunit A and catalytic subunit P. For more details see Clp protease.
3D structures of Clp protease
Updated on 20-February-2014
CLP P subunit
1tyf, 1yg6 – EcCLP – Escherichia coli
1yg8, 3hln - EcCLP (mutant)
1y7o – CLP – Streptococcus pneumoniae
1tg6 - CLP – human
2f6i, 4gm2, 4hnk - CLP – Plasmodium falciparum
2cby, 2ce3, 2c8t - CLP – Mycobacterium tuberculosis
3fes - CLP – Clostridium difficile
3ktg, 3kth, 3tt6 – BsCLP – Bacillus subtilis
3p2l - CLP – Francisella tulerensis
3q7h - CLP – Coxiella burnetii
3qwd, 3st9, 3sta, 3v5e, 4emm, 4mxi - SaCLP – Staphylococcus aureus
3v5i, 4emp - SaCLP (mutant)
2zl0 - HpCLP – Helicobacter pylori
2zl3 - HpCLP (mutant)
4jcq, 4jct – LmCLP – Listeria monocytogenes
4jcr - LmCLP (mutant)
CLP P subunit binary complex
2fzs, 3mt6 - EcCLP + peptide
2zl2 - HpCLP + peptide
2zl4 - HpCLP (mutant) + peptide
3kti, 3ktj, 3ktk - BsCLP + peptide
3tt7 - BsCLP + DFP
CLP A subunit
1k6k, 1r6c – EcCLP N terminal
1ovx - EcCLP N terminal - NMR
1ksf, 1r6b – EcCLP (mutant)
1um8 – HpCLP
CLP A subunit binary complex
1lzw, 1mg9, 1mbu, 1mbv, 1mbx – EcCLP + CLP adaptor protein ClpS
1r6o, 1r6q - EcCLP N terminal + CLP adaptor protein ClpS
