Outer surface protein
From Proteopedia
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[[1osp]], [[1fj1]] – OspA (mutant) + antibody – ''Borrelia burgdorferi''<br /> | [[1osp]], [[1fj1]] – OspA (mutant) + antibody – ''Borrelia burgdorferi''<br /> | ||
| - | [[2af5]], [[2fkg]], [[2fkj]], [[2hkd]] – OspA<br /> | + | [[2af5]], [[2fkg]], [[2fkj]], [[2hkd]], [[2oyb]] – OspA<br /> |
| - | [[2g8c]], [[2i5z]], [[2ol6]], [[2ol7]], [[2ol8]], [[2oy1]], [[2i5v]], [[2oy5]], [[2oy7]], [[2oy8]] - OspA (mutant) <br /> | + | [[2g8c]], [[2i5z]], [[2ol6]], [[2ol7]], [[2ol8]], [[2oy1]], [[2i5v]], [[2oy5]], [[2oy7]], [[2oy8]], [[2pi3]], [[3aum]], [[3cka]], [[3ckf]], [[3ckg]], [[3ec5]], [[3eex]] - OspA (mutant) <br /> |
===OspB=== | ===OspB=== | ||
[[1p4p]] – OspB C terminal<br /> | [[1p4p]] – OspB C terminal<br /> | ||
| - | [[1rjl]] - OspB+ antibody | + | [[1rjl]] - OspB+ antibody<br /> |
| + | [[2yn7]] – OspB<br /> | ||
===OspC=== | ===OspC=== | ||
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[[1ggq]], [[1g5z]] – OspC<br /> | [[1ggq]], [[1g5z]] – OspC<br /> | ||
[[1f1m]] – OspC (mutant) | [[1f1m]] – OspC (mutant) | ||
| + | |||
| + | ===OspE=== | ||
| + | |||
| + | [[2m4f]] – OspE – NMR<br /> | ||
| + | [[4j38]] – OspE + complement factor H<br /> | ||
| + | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:31, 1 April 2014
Outer surface proteins (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:
OspA -
OspB -
OspC -
OxpA, OspB and OspC -
Contents |
3D structures of outer surface protein
Updated on 01-April-2014
OspA
1osp, 1fj1 – OspA (mutant) + antibody – Borrelia burgdorferi
2af5, 2fkg, 2fkj, 2hkd, 2oyb – OspA
2g8c, 2i5z, 2ol6, 2ol7, 2ol8, 2oy1, 2i5v, 2oy5, 2oy7, 2oy8, 2pi3, 3aum, 3cka, 3ckf, 3ckg, 3ec5, 3eex - OspA (mutant)
OspB
1p4p – OspB C terminal
1rjl - OspB+ antibody
2yn7 – OspB
OspC
1ggq, 1g5z – OspC
1f1m – OspC (mutant)
OspE
2m4f – OspE – NMR
4j38 – OspE + complement factor H
