3j6b
From Proteopedia
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| - | ''' | + | ==Structure of the yeast mitochondrial large ribosomal subunit== |
| + | <StructureSection load='3j6b' size='340' side='right' caption='[[3j6b]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3j6b]] is a 40 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vw4 1vw4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J6B FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vw3|1vw3]], [[1vw4|1vw4]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j6b RCSB], [http://www.ebi.ac.uk/pdbsum/3j6b PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Mitochondria have specialized ribosomes that have diverged from their bacterial and cytoplasmic counterparts. We have solved the structure of the yeast mitoribosomal large subunit using single-particle cryo-electron microscopy. The resolution of 3.2 angstroms enabled a nearly complete atomic model to be built de novo and refined, including 39 proteins, 13 of which are unique to mitochondria, as well as expansion segments of mitoribosomal RNA. The structure reveals a new exit tunnel path and architecture, unique elements of the E site, and a putative membrane docking site. | ||
| - | + | Structure of the yeast mitochondrial large ribosomal subunit.,Amunts A, Brown A, Bai XC, Llacer JL, Hussain T, Emsley P, Long F, Murshudov G, Scheres SH, Ramakrishnan V Science. 2014 Mar 28;343(6178):1485-9. doi: 10.1126/science.1249410. PMID:24675956<ref>PMID:24675956</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| - | + | ==See Also== | |
| + | *[[Ribosome 3D structures|Ribosome 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
| + | [[Category: Amunts, A]] | ||
| + | [[Category: Bai, X C]] | ||
| + | [[Category: Brown, A]] | ||
| + | [[Category: Emsley, P]] | ||
| + | [[Category: Hussain, T]] | ||
| + | [[Category: Llacer, J L]] | ||
| + | [[Category: Long, F]] | ||
| + | [[Category: Murshudov, G]] | ||
| + | [[Category: Ramakrishnan, V]] | ||
| + | [[Category: Scheres, S H.W]] | ||
| + | [[Category: Large subunit]] | ||
| + | [[Category: Mitochondrial ribosome]] | ||
| + | [[Category: Protein-rna complex]] | ||
| + | [[Category: Ribosome]] | ||
Revision as of 08:39, 17 December 2014
Structure of the yeast mitochondrial large ribosomal subunit
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