401d
From Proteopedia
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| - | [[Image:401d.gif|left|200px]] | + | [[Image:401d.gif|left|200px]] |
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| - | '''STRUCTURE OF A DNA IN LOW SALT CONDITIONS D(GACCGCGGTC)''' | + | {{Structure |
| + | |PDB= 401d |SIZE=350|CAPTION= <scene name='initialview01'>401d</scene>, resolution 2.200Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''STRUCTURE OF A DNA IN LOW SALT CONDITIONS D(GACCGCGGTC)''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 401D is a [ | + | 401D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=401D OCA]. |
==Reference== | ==Reference== | ||
| - | X-ray crystal structures of half the human papilloma virus E2 binding site: d(GACCGCGGTC)., Finley JB, Luo M, Nucleic Acids Res. 1998 Dec 15;26(24):5719-27. PMID:[http:// | + | X-ray crystal structures of half the human papilloma virus E2 binding site: d(GACCGCGGTC)., Finley JB, Luo M, Nucleic Acids Res. 1998 Dec 15;26(24):5719-27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9838004 9838004] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Finley, J B.]] | [[Category: Finley, J B.]] | ||
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[[Category: dna double helix]] | [[Category: dna double helix]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:07:50 2008'' |
Revision as of 17:07, 20 March 2008
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| , resolution 2.200Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
STRUCTURE OF A DNA IN LOW SALT CONDITIONS D(GACCGCGGTC)
Overview
The X-ray crystal structure of the DNA decamer d(GACCGCGGTC), containing half the human papilloma virus E2 binding site, has been solved from two crystals grown at different ionic conditions (50 mM MgCl2and 50 mM spermine or 1.56 mM MgCl2and 1.56 mM spermine). Despite the variation in salt concentration, the two DNA structures are in a very similar, A-type DNA conformation, with helical axes curving towards the major groove. Although the salt concentrations do not effect the helical parameters or hydration to a large degree, there is a change in the overall helical curvature; 18 degrees and 31 degrees for the low and high salt structures, respectively. This curvature appears to be sequence specific and biologically relevant when compared with similar DNA structures, including the E2 binding site of a protein-DNA complex.
About this Structure
401D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
X-ray crystal structures of half the human papilloma virus E2 binding site: d(GACCGCGGTC)., Finley JB, Luo M, Nucleic Acids Res. 1998 Dec 15;26(24):5719-27. PMID:9838004
Page seeded by OCA on Thu Mar 20 19:07:50 2008
