Geranylgeranyl pyrophosphate synthase
From Proteopedia
| Line 1: | Line 1: | ||
| - | + | ||
{{STRUCTURE_2z4v| PDB=2z4v | SIZE=350| SCENE= |right|CAPTION=Geranylgeranyl pyrophosphate synthase dimer complex with GGPP and Mg+2 (green) [[2z4v]] }} | {{STRUCTURE_2z4v| PDB=2z4v | SIZE=350| SCENE= |right|CAPTION=Geranylgeranyl pyrophosphate synthase dimer complex with GGPP and Mg+2 (green) [[2z4v]] }} | ||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
'''Geranylgeranyl pyrophosphate synthase''' (GGPPS) catalyzes the synthesis of geranylgeranyl pyrophosphate (GGPP) from farnesyl diphosphate and isopentenyl diphosphate. GGPPS is involved in the addition of hydrophobic molecules to proteins and in the regulation of a nuclear hormone receptor. | '''Geranylgeranyl pyrophosphate synthase''' (GGPPS) catalyzes the synthesis of geranylgeranyl pyrophosphate (GGPP) from farnesyl diphosphate and isopentenyl diphosphate. GGPPS is involved in the addition of hydrophobic molecules to proteins and in the regulation of a nuclear hormone receptor. | ||
Revision as of 09:41, 18 August 2014
Geranylgeranyl pyrophosphate synthase (GGPPS) catalyzes the synthesis of geranylgeranyl pyrophosphate (GGPP) from farnesyl diphosphate and isopentenyl diphosphate. GGPPS is involved in the addition of hydrophobic molecules to proteins and in the regulation of a nuclear hormone receptor.
3D Structures of geranylgeranyl pyrophosphate synthase
Updated on 18-August-2014
2dh4 – yGGPPS + Mg - yeast
2e8t – yGGPPS + Mg + isopentenyl pyrophosphate + farnesyl thiopyrophosphate
2e8u, 2e8w – yGGPPS + Mg + isopentenyl pyrophosphate
2e8v – yGGPPS + GGPP
2z4v – yGGPPS + GGPP + Mg
2e8x – yGGPPS + GPP + Mg
2e90 – yGGPPS + Mg + PP + farnesyl pyrophosphate
2e91, 2e92, 2e93, 2e94, 2e95, 2z7h, 2z4w, 2z4x, 2z4y, 2z4z, 2z50, 2z52, 2z78, 2z7i, 2zeu – yGGPPS + Mg + inhibitor
2zev – yGGPPS + Mg + isopentenyl pyrophosphate + inhibitor
2q80 – GGPPS + GGPP + Mg - human
2azj – SsGGPPS – Sulfolobus solfataricus
2azk – SsGGPPS (mutant)
3lk5 – CgGGPPS – Corynebacterium glutamicum
3n3d, 3pko – GGPPS – Lactobacillus brevis
2j1o – SaGGPPS – Sinapis alba
2j1p – SaGGPPS + GGPP
3qqv – CgGGPPS + isoprenyl diphosphate
