4jxw

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'''Unreleased structure'''
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==X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a non-covalent inhibitor 3-{[3-(4-CARBOXYPHENYL)PROPYL]SULFAMOYL}THIOPHENE-2-CARBOXYLIC ACID (compound 6)==
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<StructureSection load='4jxw' size='340' side='right' caption='[[4jxw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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The entry 4jxw is ON HOLD until Jul 02 2015
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4jxw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JXW OCA]. <br>
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Authors: Powers, R.A., Hendershot, J.M.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1MW:3-{[3-(4-CARBOXYPHENYL)PROPYL]SULFAMOYL}THIOPHENE-2-CARBOXYLIC+ACID'>1MW</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jxs|4jxs]], [[4jxv|4jxv]], [[1xgi|1xgi]], [[1xgj|1xgj]], [[1l2s|1l2s]]</td></tr>
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Description:
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jxw RCSB], [http://www.ebi.ac.uk/pdbsum/4jxw PDBsum]</span></td></tr>
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<table>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Hendershot, J M.]]
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[[Category: Powers, R A.]]
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[[Category: Beta-lactamase]]
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[[Category: Cephalosporinase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine hydrolase]]

Revision as of 08:19, 7 May 2014

X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a non-covalent inhibitor 3-{[3-(4-CARBOXYPHENYL)PROPYL]SULFAMOYL}THIOPHENE-2-CARBOXYLIC ACID (compound 6)

4jxw, resolution 2.30Å

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