4jk0

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{{STRUCTURE_4jk0| PDB=4jk0 | SCENE= }}
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==Crystal structure of T89Q-mutant of RNA silencing suppressor p19 with 2nt-5'-overhanging double-helical RNA 21mer pUUUG(CUG)5CU==
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===Crystal structure of T89Q-mutant of RNA silencing suppressor p19 with 2nt-5'-overhanging double-helical RNA 21mer pUUUG(CUG)5CU===
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<StructureSection load='4jk0' size='340' side='right' caption='[[4jk0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4jk0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tbsv Tbsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JK0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jgn|4jgn]], [[4j39|4j39]], [[1r9f|1r9f]], [[4e48|4e48]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jk0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jk0 RCSB], [http://www.ebi.ac.uk/pdbsum/4jk0 PDBsum]</span></td></tr>
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</table>
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== Function ==
[[http://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK]] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
[[http://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK]] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
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==About this Structure==
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==See Also==
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[[4jk0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JK0 OCA].
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*[[P19|P19]]
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[[Category: Katorcha, E.]]
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*[[RNA silencing suppressor|RNA silencing suppressor]]
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[[Category: Malinina, L.]]
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__TOC__
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[[Category: Popov, A N.]]
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</StructureSection>
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[[Category: Tamjar, J.]]
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[[Category: Tbsv]]
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[[Category: Katorcha, E]]
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[[Category: Malinina, L]]
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[[Category: Popov, A N]]
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[[Category: Tamjar, J]]
[[Category: Dimer]]
[[Category: Dimer]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]

Revision as of 19:46, 25 December 2014

Crystal structure of T89Q-mutant of RNA silencing suppressor p19 with 2nt-5'-overhanging double-helical RNA 21mer pUUUG(CUG)5CU

4jk0, resolution 2.30Å

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