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4tln
From Proteopedia
(Difference between revisions)
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| - | [[Image:4tln.jpg|left|200px]] | + | [[Image:4tln.jpg|left|200px]] |
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| - | '''BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS''' | + | {{Structure |
| + | |PDB= 4tln |SIZE=350|CAPTION= <scene name='initialview01'>4tln</scene>, resolution 2.3Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=LNO:L-LEUCYL-HYDROXYLAMINE'>LNO</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 4TLN is a [ | + | 4TLN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLN OCA]. |
==Reference== | ==Reference== | ||
| - | Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis., Holmes MA, Matthews BW, Biochemistry. 1981 Nov 24;20(24):6912-20. PMID:[http:// | + | Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis., Holmes MA, Matthews BW, Biochemistry. 1981 Nov 24;20(24):6912-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7317361 7317361] |
[[Category: Bacillus thermoproteolyticus]] | [[Category: Bacillus thermoproteolyticus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: hydrolase (metalloproteinase)]] | [[Category: hydrolase (metalloproteinase)]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:11:14 2008'' |
Revision as of 17:11, 20 March 2008
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| , resolution 2.3Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , and | ||||||
| Activity: | Thermolysin, with EC number 3.4.24.27 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
About this Structure
4TLN is a Single protein structure of sequence from Bacillus thermoproteolyticus. Full crystallographic information is available from OCA.
Reference
Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis., Holmes MA, Matthews BW, Biochemistry. 1981 Nov 24;20(24):6912-20. PMID:7317361
Page seeded by OCA on Thu Mar 20 19:11:14 2008
