4nd7

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{{STRUCTURE_4nd7| PDB=4nd7 | SCENE= }}
{{STRUCTURE_4nd7| PDB=4nd7 | SCENE= }}
===Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the closed form===
===Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the closed form===
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{{ABSTRACT_PUBMED_24611875}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
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[[4nd7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ND7 OCA].
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[[4nd7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ND7 OCA].
==Reference==
==Reference==
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<references group="xtra"/><references/>
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<ref group="xtra">PMID:024611875</ref><references group="xtra"/><references/>
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[[Category: Metja]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Cooley, R B.]]
[[Category: Cooley, R B.]]

Revision as of 08:29, 16 April 2014

Template:STRUCTURE 4nd7

Contents

Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the closed form

Template:ABSTRACT PUBMED 24611875

Function

[SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[1]

About this Structure

4nd7 is a 1 chain structure with sequence from Metja. Full crystallographic information is available from OCA.

Reference

  • Cooley RB, Feldman JL, Driggers CM, Bundy TA, Stokes AL, Karplus PA, Mehl RA. Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases. Biochemistry. 2014 Apr 1;53(12):1916-24. doi: 10.1021/bi5001239. Epub 2014 Mar, 20. PMID:24611875 doi:http://dx.doi.org/10.1021/bi5001239
  1. ↑ Steer BA, Schimmel P. Major anticodon-binding region missing from an archaebacterial tRNA synthetase. J Biol Chem. 1999 Dec 10;274(50):35601-6. PMID:10585437

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