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== Catalytic triad ==
== Catalytic triad ==
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MGL has a classic catalytic triad that contains Ser-His-Asp. This triad has a natural attraction to Endocannabinoids, specifically 2-arachidonylglycerol (2-AG). 2-AG contributes to brain signals (neurons) to suppress the pain pathways when a patient is feeling depressed or suffering from any type of pain.
[[Image:Catalytic_triad.png|right|250px|thumb|Catalytic Triad of MGL structure]]
[[Image:Catalytic_triad.png|right|250px|thumb|Catalytic Triad of MGL structure]]
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====Binding====
====Binding====

Revision as of 02:26, 24 March 2014

Monoglyceride Lipase (MGL)

Secondary structure of MGL

Drag the structure with the mouse to rotate
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