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Mandelate dehydrogenase
From Proteopedia
(Difference between revisions)
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<StructureSection load='2a7p' size='400' side='right' caption='Structure of monomer of S-mandelate dehydrogenase tetramer complex with 3-indoleacetate and flavin mononucleotide (PDB entry [[2a7p]])' scene=''> | <StructureSection load='2a7p' size='400' side='right' caption='Structure of monomer of S-mandelate dehydrogenase tetramer complex with 3-indoleacetate and flavin mononucleotide (PDB entry [[2a7p]])' scene=''> | ||
| - | + | == Function == | |
| - | '''S-mandelate dehydrogenase''' (SMD) catalyzes the conversion of S-2-hydroxy-2-phenylacetate and acceptor to 2-oxo-2-phenylacetate and reduced acceptor. SMD is a FMN-dependent enzyme. D-mandelate dehydrogenase (DMD) catalyzes the NAD-dependent oxidation of D-mandalate to phenylglyoxylate. | + | '''S-mandelate dehydrogenase''' (SMD) catalyzes the conversion of S-2-hydroxy-2-phenylacetate and acceptor to 2-oxo-2-phenylacetate and reduced acceptor<ref>PMID:10231535</ref>. SMD is a FMN-dependent enzyme. '''D-mandelate dehydrogenase''' (DMD) catalyzes the NAD-dependent oxidation of D-mandalate to phenylglyoxylate. |
==3D structures of mandelate dehydrogenase== | ==3D structures of mandelate dehydrogenase== | ||
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[[2a85]] – PpSMD (mutant) + 2-hydroxyoctanoate<br /> | [[2a85]] – PpSMD (mutant) + 2-hydroxyoctanoate<br /> | ||
[[2w2k]] - RgDMD<br /> | [[2w2k]] - RgDMD<br /> | ||
| + | == References == | ||
| + | <references/> | ||
| - | </StructureSection> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:45, 17 April 2016
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