Metabotropic glutamate receptor

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[[3mq4]] – hMGluR7 ligand-binding domain + antagonist<br />
[[3mq4]] – hMGluR7 ligand-binding domain + antagonist<br />
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==See Also==
==See Also==
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[[Category:Topic Page]]
[[Category:Topic Page]]
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Revision as of 08:19, 19 August 2014

Metabotropic glutamate receptors are glutamate receptors that activate ion channels indirectly through a signalling cascade involving G proteins. They are members of the large class of seven-transmembrane domain receptors, the G protein-coupled receptors.

Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamateand gadolinium ions (1isr)

Drag the structure with the mouse to rotate

Articles in Proteopedia concerning Toll-like Receptors include:


Contents

3D structures of metabotropic glutamate receptor

Updated on 19-August-2014

Metabotropic glutamate receptor 1

1ewt, 1ewv - rMGluR1 ligand-binding domain
3ks9 – hMGluR1 (mutant) + antagonist
4or2 - hMGluR1/cytochrome b526
1isr, 1ewk – rMGluR1 ligand-binding domain + Glu
1iss - rMGluR1 ligand-binding domain + antagonist

Metabotropic glutamate receptor 3

2e4u – hMGluR3 ligand-binding domain (mutant) + Glu
2e4v, 2e4w, 2e4x, 2e4y, 2e4z - hMGluR3 ligand-binding domain (mutant) + agonist
3sm9 - hMGluR3 + antagonist

Metabotropic glutamate receptor 5

3lmk – hMGluR5 ligand-binding domain (mutant) + positive allosteric modulator + Glu

Metabotropic glutamate receptor 7

3mq4 – hMGluR7 ligand-binding domain + antagonist

See Also

[Membrane Channels & Pumps]]
Ionotropic_Glutamate_Receptors
Alzheimer's Disease

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