Molecular Playground/ClyA

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[[1QOY]] is a monomer from the dodecameric pore-forming toxin from [http://en.wikipedia.org/wiki/Escherichia_coli ''Escherichia coli'']. It is comprised of four alpha helicies and a smaller fifth alpha helix.
[[1QOY]] is a monomer from the dodecameric pore-forming toxin from [http://en.wikipedia.org/wiki/Escherichia_coli ''Escherichia coli'']. It is comprised of four alpha helicies and a smaller fifth alpha helix.
Though its crystal structure,[[2WCD]] revealed a dodecamer, larger [http://pubs.acs.org/doi/abs/10.1021/ja4053398 pores] have been isolated, as well.
Though its crystal structure,[[2WCD]] revealed a dodecamer, larger [http://pubs.acs.org/doi/abs/10.1021/ja4053398 pores] have been isolated, as well.
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[[Image:ClyA.png]]
[[Image:ClyA.png]]
==Research on ClyA at UMass Amherst==
==Research on ClyA at UMass Amherst==
The Chen Lab, in collaboration with the Heuck lab, recently published a paper on [http://www.jbc.org/content/288/43/31042.short, ClyA] assembly.
The Chen Lab, in collaboration with the Heuck lab, recently published a paper on [http://www.jbc.org/content/288/43/31042.short, ClyA] assembly.

Revision as of 16:32, 26 March 2014

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