User:Daud Akhtar/Sandbox 1
From Proteopedia
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<scene name='58/580852/Ligand/3'>Ligands on each respective subunit of G6PD</scene> | <scene name='58/580852/Ligand/3'>Ligands on each respective subunit of G6PD</scene> | ||
| + | ==Glucose-6-Phosphate Dehydrogenase Deficiency | ||
| + | ===Classification=== | ||
| + | The [[World Health Organization]] classifies G6PD genetic variants into five classes, the first three of which are deficiency states.<ref>{{cite journal|last=WHO Working Group|title=Glucose-6-phosphate dehydrogenase deficiency.|journal=Bulletin of the World Health Organization|year=1989|volume=67|issue=6|pages=601–11|pmid=2633878}}</ref> | ||
| + | # Severe deficiency (<10% activity) with chronic (nonspherocytic) hemolytic anemia | ||
| + | # Severe deficiency (<10% activity), with intermittent hemolysis | ||
| + | # Mild deficiency (10-60% activity), hemolysis with stressors only | ||
| + | # Non-deficient variant, no clinical sequelae | ||
| + | # Increased enzyme activity, no clinical sequelae | ||
Revision as of 23:02, 28 March 2014
Your Heading Here (maybe something like 'Structure')
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Glucose 6 Phosphate Dehydrognease
References
- ↑ Salati LM, Amir-Ahmady B. Dietary regulation of expression of glucose-6-phosphate dehydrogenase. Annu Rev Nutr. 2001;21:121-40. PMID:11375432 doi:http://dx.doi.org/10.1146/annurev.nutr.21.1.121
- ↑ <ref>PMID:9556453</ref>
