NEDD8
From Proteopedia
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{{STRUCTURE_1ndd| PDB=1ndd | SIZE=400| SCENE= |right|CAPTION=Human NEDD8 complex with sulfate and Cl- (green) ions, [[1ndd]] }} | {{STRUCTURE_1ndd| PDB=1ndd | SIZE=400| SCENE= |right|CAPTION=Human NEDD8 complex with sulfate and Cl- (green) ions, [[1ndd]] }} | ||
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[[NEDD8]] is a ubiquitin-like protein in human. It facilitates ubiquitin conjugation. It participates in the recruitment of E2 to the ubiquitin ligase complex. NEDD8 modifies the cullin subunits (CUL) of SCF ubiquitin E3 ligase. In yeast the protein is called Rub1. The images at the left and at the right correspond to one representative NEDD8, ''i.e.'' the crystal structure of NEDD8 ([[1ndd]]). Cl and SO4 are shown as space filling objects. | [[NEDD8]] is a ubiquitin-like protein in human. It facilitates ubiquitin conjugation. It participates in the recruitment of E2 to the ubiquitin ligase complex. NEDD8 modifies the cullin subunits (CUL) of SCF ubiquitin E3 ligase. In yeast the protein is called Rub1. The images at the left and at the right correspond to one representative NEDD8, ''i.e.'' the crystal structure of NEDD8 ([[1ndd]]). Cl and SO4 are shown as space filling objects. | ||
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== 3D Structures of NEDD8 == | == 3D Structures of NEDD8 == | ||
Revision as of 08:53, 19 August 2014
NEDD8 is a ubiquitin-like protein in human. It facilitates ubiquitin conjugation. It participates in the recruitment of E2 to the ubiquitin ligase complex. NEDD8 modifies the cullin subunits (CUL) of SCF ubiquitin E3 ligase. In yeast the protein is called Rub1. The images at the left and at the right correspond to one representative NEDD8, i.e. the crystal structure of NEDD8 (1ndd). Cl and SO4 are shown as space filling objects.
Contents |
3D Structures of NEDD8
Updated on 19-August-2014
NEDD8
1ndd - hNEDD8 - human
2ko3 – hNEDD8 – NMR
NEDD8+ubiquitin-activating enzyme E1
3gzn – hNEDD8+hE1 regulatory and catalytic subunits
3dbh, 3dbl, 3dbr - hNEDD8+hE1 regulatory and catalytic subunits (mutant)
2nvu - hNEDD8+hE1 regulatory subunit+MBP/E1 catalytic subunit+UBC12
1r4m - hNEDD8+hE1C+amyloid beta precursor protein
1r4n - hNEDD8+hE1C+amyloid beta precursor protein+ATP
NEDD8+other proteins
3dqv – hNEDD8+CUL-5
2bkr – hNEDD8+NEDP1
1xt9 – hNEDD8+DEN1
4f8c – hNEDD8 + cycle inhibiting factor
4hcp – hNEDD8 + ATP/GTP binding protein
Rub1
1bt0 – Rub1 – Arabidopsis thaliana
