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Outer surface protein
From Proteopedia
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*[[Highlighted Proteins of Lyme Disease]]<br /> | *[[Highlighted Proteins of Lyme Disease]]<br /> | ||
| + | ==3D structures of Outer surface proteins (Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}) == | ||
| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | * OspA | |
| + | ** [[1osp]], [[1fj1]] – OspA (mutant) + antibody – ''Borrelia burgdorferi''<br /> | ||
| + | ** [[2af5]], [[2fkg]], [[2fkj]], [[2hkd]], [[2oyb]] – OspA<br /> | ||
| + | ** [[2g8c]], [[2i5z]], [[2ol6]], [[2ol7]], [[2ol8]], [[2oy1]], [[2i5v]], [[2oy5]], [[2oy7]], [[2oy8]], [[2pi3]], [[3aum]], [[3cka]], | ||
| + | ** [[3ckf]], [[3ckg]], [[3ec5]], [[3eex]] - OspA (mutant) <br /> | ||
| - | + | * OspB | |
| + | ** [[1p4p]] – OspB C terminal<br /> | ||
| + | ** [[1rjl]] - OspB+ antibody<br /> | ||
| + | ** [[2yn7]] – OspB<br /> | ||
| - | + | * OspC | |
| + | ** [[1ggq]], [[1g5z]] – OspC<br /> | ||
| + | ** [[1f1m]] – OspC (mutant) | ||
| - | + | * OspE | |
| - | + | ** [[2m4f]] – OspE – NMR<br /> | |
| - | + | ** [[4j38]] – OspE + complement factor H<br /> | |
| - | + | }} | |
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| - | [[2m4f]] – OspE – NMR<br /> | + | |
| - | [[4j38]] – OspE + complement factor H<br /> | + | |
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 15:16, 29 October 2014
Outer surface proteins (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:
OspA -
OspB -
OspC -
OxpA, OspB and OspC -
