This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4pwy
From Proteopedia
(Difference between revisions)
m (Protected "4pwy" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | {{STRUCTURE_4pwy| PDB=4pwy | SCENE= }} | |
| + | ===Crystal structure of a Calmodulin-lysine N-methyltransferase fragment=== | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome. | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4pwy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWY OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <references group="xtra"/><references/> | ||
| + | [[Category: Calmodulin-lysine N-methyltransferase]] | ||
| + | [[Category: Arrowsmith, C H.]] | ||
| + | [[Category: Bountra, C.]] | ||
| + | [[Category: Brown, P J.]] | ||
| + | [[Category: Edwards, A M.]] | ||
| + | [[Category: Hong, B S.]] | ||
| + | [[Category: Li, Y.]] | ||
| + | [[Category: SGC, Structural Genomics Consortium.]] | ||
| + | [[Category: Tempel, W.]] | ||
| + | [[Category: Walker, J R.]] | ||
| + | [[Category: Methyl transferase]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Structural genomics consortium]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 10:12, 16 April 2014
Contents |
Crystal structure of a Calmodulin-lysine N-methyltransferase fragment
Disease
[CMKMT_HUMAN] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome.
Function
[CMKMT_HUMAN] Catalyzes the trimethylation of 'Lys-116' in calmodulin.[1]
About this Structure
4pwy is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Magnani R, Dirk LM, Trievel RC, Houtz RL. Calmodulin methyltransferase is an evolutionarily conserved enzyme that trimethylates Lys-115 in calmodulin. Nat Commun. 2010 Jul 27;1:43. doi: 10.1038/ncomms1044. PMID:20975703 doi:http://dx.doi.org/10.1038/ncomms1044
