2rf3

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[[Image:2rf3.jpg|left|200px]]<br /><applet load="2rf3" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2rf3.jpg|left|200px]]
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caption="2rf3, resolution 1.75&Aring;" />
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'''Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles'''<br />
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{{Structure
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|PDB= 2rf3 |SIZE=350|CAPTION= <scene name='initialview01'>2rf3</scene>, resolution 1.75&Aring;
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|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+B+308'>AC1</scene> and <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+309'>AC2</scene>
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2RF3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=SPM:'>SPM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+B+308'>AC1</scene> and <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+309'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF3 OCA].
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2RF3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF3 OCA].
==Reference==
==Reference==
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Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles., Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M, Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18253536 18253536]
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Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles., Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M, Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18253536 18253536]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Egli, M.]]
[[Category: Egli, M.]]
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[[Category: x-ray crystal structure]]
[[Category: x-ray crystal structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 27 07:47:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:28 2008''

Revision as of 16:35, 20 March 2008

Image:2rf3.jpg


PDB ID 2rf3

Drag the structure with the mouse to rotate
, resolution 1.75Å
Sites: and
Ligands: and
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles


Overview

The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

About this Structure

2RF3 is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles., Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M, Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:18253536

Page seeded by OCA on Thu Mar 20 18:35:28 2008

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