Phosphoserine phosphatase

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===Phosphoserine phosphatase===
[[2j70]], [[1w53]] – BsPSP RsbT binding domain – ''Bacillus subtilis''<br />
[[2j70]], [[1w53]] – BsPSP RsbT binding domain – ''Bacillus subtilis''<br />
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[[4ij5]] – HtPSP – ''Hydrogenobacter thermophilus''<br />
[[4ij5]] – HtPSP – ''Hydrogenobacter thermophilus''<br />
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'''Phosphoserine phosphatase binary complex'''
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===Phosphoserine phosphatase binary complex===
[[3p96]] – PSP + Mg – ''Mycobacterium avium''<br />
[[3p96]] – PSP + Mg – ''Mycobacterium avium''<br />
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[[4ij6]] – HtPSP (mutant) + phosphoserine<br />
[[4ij6]] – HtPSP (mutant) + phosphoserine<br />
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'''Phosphoserine phosphatase ternary complex'''
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===Phosphoserine phosphatase ternary complex===
[[1f5s]], [[1j97]], [[1l7m]] – MjPSP + PO4 + Mg<br />
[[1f5s]], [[1j97]], [[1l7m]] – MjPSP + PO4 + Mg<br />

Revision as of 08:45, 2 September 2014

Phosphoserine phosphatase dimer complex with phosphoserine 1l8o

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Phosphoserine phosphatase (PSP) catalyzes the dephosphorylation of phosphoserine to produce serine and phosphate. This is the last reaction in serine biosynthesis. PSP is part of the glycine, serine and threonine metabolism. Mg+2 ion is a cofactor of PSP.

Contents

3D structures of phosphoserine phosphatase

Updated on 02-September-2014

Phosphoserine phosphatase

2j70, 1w53 – BsPSP RsbT binding domain – Bacillus subtilis
2j6z, 2j6y - BsPSP RsbT binding domain (mutant)
4b6j – ToPSP – Thermococcus onnurineus
4ij5 – HtPSP – Hydrogenobacter thermophilus

Phosphoserine phosphatase binary complex

3p96 – PSP + Mg – Mycobacterium avium
3m1y – PSP + Mg – Helicobacter pylori
1l7o – MjPSP (mutant) + Zn – Methanocaldococcus jannaschii
1l8l – hPSP (mutant) + phosphono-propionic acid – human
1l8o – hPSP (mutant) + PO4
1nnl – hPSP + Ca
3w40, 3w41 – BsPSP + Mg
3w42, 3w43, 3w44 – BsPSP + Mn
3w45 – BsPSP + Co
4ap9 – ToPSP + pyridine derivative
4ij6 – HtPSP (mutant) + phosphoserine

Phosphoserine phosphatase ternary complex

1f5s, 1j97, 1l7m – MjPSP + PO4 + Mg
1l7n – MjPSP + AlF4 + Mg
1l7p – MjPSP (mutant) + phosphoserine + PO4

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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