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4p2h

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'''Unreleased structure'''
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==Structure of human DNA polymerase complexed with N7MG in the template opposite to incoming non-hydrolyzable TTP with manganese in the active site==
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<StructureSection load='4p2h' size='340' side='right' caption='[[4p2h]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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The entry 4p2h is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4p2h]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P2H FirstGlance]. <br>
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Authors: Lee, S., Koag, M.C.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1FZ:5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]THYMIDINE'>1FZ</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMG:2-AMINO-9-(2-DEOXY-2-FLUORO-5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-7-METHYL-6-OXO-6,9-DIHYDRO-1H-PURIN-7-IUM'>FMG</scene></td></tr>
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Description: Structure of human DNA polymerase complexed with N7MG in the template opposite to incoming non-hydrolyzable TTP with manganese in the active site
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bpx|1bpx]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p2h RCSB], [http://www.ebi.ac.uk/pdbsum/4p2h PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Koag, M C.]]
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[[Category: Lee, S.]]
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[[Category: Dna binding]]
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[[Category: Dna polymerase fold]]
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[[Category: Nucleotidyl transfer]]
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[[Category: Transferase-dna complex]]

Revision as of 06:35, 25 June 2014

Structure of human DNA polymerase complexed with N7MG in the template opposite to incoming non-hydrolyzable TTP with manganese in the active site

4p2h, resolution 1.99Å

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