1vw3

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{{Large structure}}
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==Structure of the yeast mitochondrial large ribosomal subunit==
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{{STRUCTURE_1vw3| PDB=1vw3 | SCENE= }}
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<StructureSection load='1vw3' size='340' side='right' caption='[[1vw3]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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===Structure of the yeast mitochondrial large ribosomal subunit===
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== Structural highlights ==
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{{ABSTRACT_PUBMED_24675956}}
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<table><tr><td colspan='2'>[[1vw3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VW3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j6b|3j6b]], [[1vw4|1vw4]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vw3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vw3 PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Mitochondria have specialized ribosomes that have diverged from their bacterial and cytoplasmic counterparts. We have solved the structure of the yeast mitoribosomal large subunit using single-particle cryo-electron microscopy. The resolution of 3.2 angstroms enabled a nearly complete atomic model to be built de novo and refined, including 39 proteins, 13 of which are unique to mitochondria, as well as expansion segments of mitoribosomal RNA. The structure reveals a new exit tunnel path and architecture, unique elements of the E site, and a putative membrane docking site.
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==About this Structure==
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Structure of the yeast mitochondrial large ribosomal subunit.,Amunts A, Brown A, Bai XC, Llacer JL, Hussain T, Emsley P, Long F, Murshudov G, Scheres SH, Ramakrishnan V Science. 2014 Mar 28;343(6178):1485-9. doi: 10.1126/science.1249410. PMID:24675956<ref>PMID:24675956</ref>
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[[1vw3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VW3 OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<ref group="xtra">PMID:024675956</ref><references group="xtra"/><references/>
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</div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Amunts, A.]]
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[[Category: Amunts, A]]
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[[Category: Bai, X C.]]
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[[Category: Bai, X C]]
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[[Category: Brown, A.]]
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[[Category: Brown, A]]
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[[Category: Emsley, P.]]
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[[Category: Emsley, P]]
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[[Category: Hussain, T.]]
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[[Category: Hussain, T]]
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[[Category: Llacer, J L.]]
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[[Category: Llacer, J L]]
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[[Category: Long, F.]]
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[[Category: Long, F]]
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[[Category: Murshudov, G.]]
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[[Category: Murshudov, G]]
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[[Category: Ramakrishnan, V.]]
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[[Category: Ramakrishnan, V]]
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[[Category: Scheres, S H.W.]]
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[[Category: Scheres, S H.W]]
[[Category: Large subunit]]
[[Category: Large subunit]]
[[Category: Mitochondrial ribosome]]
[[Category: Mitochondrial ribosome]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]
[[Category: Ribosome]]
[[Category: Ribosome]]

Revision as of 10:51, 19 November 2014

Structure of the yeast mitochondrial large ribosomal subunit

1vw3, resolution 3.20Å

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