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Plasminogen activator
From Proteopedia
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[[1tpm]], [[1tpn]] - hTPA fibrin-binding domain – NMR | [[1tpm]], [[1tpn]] - hTPA fibrin-binding domain – NMR | ||
| - | ==Urokinase-type plasminogen activator [[Urokinase]] | + | ==Urokinase-type plasminogen activator== |
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| + | [[Urokinase]] | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:04, 9 April 2014
Plasminogen activator (PLA) is a serine protease which converts plasminogen to plasmin. It includes Tissue PLA (TPA) which is involved in breakdown of blood clots and urokinase-type PLA Urokinase. TPA structure contains heavy and light chains (HC, LC). PLA is inhibited by PLA inhibitor 1 and 2.
Contents |
3D structures of plasminogen activator
Updated on 09-April-2014
1a5i – PLA residues 213-477 + EGR-CMK – Vampire bat
1bqy – PLA – Pit viper
Tissue plasminogen activator
1a5h – hTPA HC+LC + benzamidine – human
1rtf - hTPA HC+LC
1tpg – hTPA F1-G - NMR
1bda – hTPA catalytic domain (mutant) + EGR-CMK
1pk2 – hTPA kringle 2 domain + 6-aminohexanoic acid – NMR
1tpk, 1pml - hTPA kringle 2 domain
1kdu - hTPA kringle domain – NMR
1tpm, 1tpn - hTPA fibrin-binding domain – NMR
