4p90

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'''Unreleased structure'''
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==Crystal structure of the kinase domain of human PAK1 in complex with compound 15==
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<StructureSection load='4p90' size='340' side='right' caption='[[4p90]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
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The entry 4p90 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4p90]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P90 FirstGlance]. <br>
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Authors: Ferguson, A.D.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2K0:[2-CHLORO-5-(HYDROXYMETHYL)PHENYL]{5-[1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}METHANONE'>2K0</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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Description: Crystal structure of the kinase domain of human PAK1 in complex with compound 15
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p90 RCSB], [http://www.ebi.ac.uk/pdbsum/4p90 PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Ferguson, A D.]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 10:11, 10 September 2014

Crystal structure of the kinase domain of human PAK1 in complex with compound 15

4p90, resolution 2.49Å

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