4pyp
From Proteopedia
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| - | ''' | + | ==Crystal structure of the human glucose transporter GLUT1== |
| - | + | <StructureSection load='4pyp' size='340' side='right' caption='[[4pyp]], [[Resolution|resolution]] 3.17Å' scene=''> | |
| - | The entry | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[4pyp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PYP FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pyp RCSB], [http://www.ebi.ac.uk/pdbsum/4pyp PDBsum]</span></td></tr> | |
| - | + | <table> | |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/GTR1_HUMAN GTR1_HUMAN]] Hereditary cryohydrocytosis with reduced stomatin;Paroxysmal exertion-induced dyskinesia;Encephalopathy due to GLUT1 deficiency;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Childhood absence epilepsy;Epilepsy with myoclonic-astatic seizures. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GTR1_HUMAN GTR1_HUMAN]] Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Deng, D.]] | ||
| + | [[Category: Hu, M X.]] | ||
| + | [[Category: Sun, P C.]] | ||
| + | [[Category: Wu, J P.]] | ||
| + | [[Category: Xu, C.]] | ||
| + | [[Category: Yan, C Y.]] | ||
| + | [[Category: Yan, N.]] | ||
| + | [[Category: Glycosylation]] | ||
| + | [[Category: Helix]] | ||
| + | [[Category: Membrane transporter]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 09:28, 21 May 2014
Crystal structure of the human glucose transporter GLUT1
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Categories: Deng, D. | Hu, M X. | Sun, P C. | Wu, J P. | Xu, C. | Yan, C Y. | Yan, N. | Glycosylation | Helix | Membrane transporter | Transport protein
