4pwy
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of a Calmodulin-lysine N-methyltransferase fragment== | |
| - | === | + | <StructureSection load='4pwy' size='340' side='right' caption='[[4pwy]], [[Resolution|resolution]] 1.90Å' scene=''> |
| - | + | == Structural highlights == | |
| - | ==Disease== | + | <table><tr><td colspan='2'>[[4pwy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PWY FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAMKMT, C2orf34, CLNMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calmodulin-lysine_N-methyltransferase Calmodulin-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.60 2.1.1.60] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pwy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pwy RCSB], [http://www.ebi.ac.uk/pdbsum/4pwy PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome. | [[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome. | ||
| - | + | == Function == | |
| - | ==Function== | + | |
[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref> | [[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref> | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | <references | + | |
[[Category: Calmodulin-lysine N-methyltransferase]] | [[Category: Calmodulin-lysine N-methyltransferase]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Human]] |
| - | [[Category: Bountra, C | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Brown, P J | + | [[Category: Bountra, C]] |
| - | [[Category: Edwards, A M | + | [[Category: Brown, P J]] |
| - | [[Category: Hong, B S | + | [[Category: Edwards, A M]] |
| - | [[Category: Li, Y | + | [[Category: Hong, B S]] |
| - | [[Category: | + | [[Category: Li, Y]] |
| - | [[Category: Tempel, W | + | [[Category: Structural genomic]] |
| - | [[Category: Walker, J R | + | [[Category: Tempel, W]] |
| + | [[Category: Walker, J R]] | ||
[[Category: Methyl transferase]] | [[Category: Methyl transferase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 08:43, 5 January 2015
Crystal structure of a Calmodulin-lysine N-methyltransferase fragment
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