2gq4

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{{STRUCTURE_2gq4| PDB=2gq4 | SCENE= }}
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==Crystal structure of an RNA racemate==
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===Crystal structure of an RNA racemate===
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<StructureSection load='2gq4' size='340' side='right' caption='[[2gq4]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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{{ABSTRACT_PUBMED_16699193}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2gq4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQ4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GQ4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=0C:L-CYTIDINE-5-MONOPHOSPHATE'>0C</scene>, <scene name='pdbligand=0G:L-GUANOSINE-5-MONOPHOSPHATE'>0G</scene>, <scene name='pdbligand=0U:L-URIDINE-5-MONOPHOSPHATE'>0U</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2g32|2g32]], [[2gpm|2gpm]], [[2gq5|2gq5]], [[2gq6|2gq6]], [[2gq7|2gq7]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gq4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gq4 RCSB], [http://www.ebi.ac.uk/pdbsum/2gq4 PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The racemate of the RNA duplex r(CUGGGCGG).r(CCGCCUGG) from Thermus flavus 5S rRNA has been crystallized and examined by X-ray crystallography. The space group is P1(_) with approximate unit-cell parameters a = 26.5, b = 38.0, c = 45.4 Angstrom, alpha = 113.1, beta = 100.5, gamma = 93.3 degrees. The structure was solved by molecular replacement. There are four RNA duplexes in the unit cell. The crystal lattice consists of columns of RNA duplexes. The duplexes are stacked end-to-end and are stabilized by intermolecular base-stacking interactions. Within each column the L-duplexes and D-duplexes are stacked alternately. Every other duplex in each stack has two alternative conformations, approximately equally occupied, corresponding to molecules oriented in opposite directions. Neighbouring columns are related by the crystallographic centre of symmetry. The unit cell also contains approximately 250 ordered water molecules and six ordered calcium ions. A glycerol molecule is visible in the minor groove interacting with a guanosine residue.
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==About this Structure==
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The first crystal structure of an RNA racemate.,Rypniewski W, Vallazza M, Perbandt M, Klussmann S, Delucas LJ, Betzel C, Erdmann VA Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):659-64. Epub 2006, May 12. PMID:16699193<ref>PMID:16699193</ref>
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[[2gq4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQ4 OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<ref group="xtra">PMID:016699193</ref><references group="xtra"/><references/>
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</div>
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[[Category: Betzel, C.]]
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== References ==
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[[Category: Erdmann, V A.]]
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<references/>
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[[Category: Klussmann, S.]]
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__TOC__
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[[Category: Perbandt, M.]]
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</StructureSection>
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[[Category: Rypniewski, W.]]
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[[Category: Betzel, C]]
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[[Category: Vallazza, M.]]
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[[Category: Erdmann, V A]]
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[[Category: Klussmann, S]]
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[[Category: Perbandt, M]]
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[[Category: Rypniewski, W]]
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[[Category: Vallazza, M]]
[[Category: Deouble helix]]
[[Category: Deouble helix]]
[[Category: Racemate]]
[[Category: Racemate]]
[[Category: Rna]]
[[Category: Rna]]

Revision as of 06:28, 22 December 2014

Crystal structure of an RNA racemate

2gq4, resolution 1.35Å

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