2b8q

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Revision as of 08:32, 23 April 2014

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Template:STRUCTURE 2b8q

Contents 1 X-ray structure of Acanthamoeba ployphaga mimivirus nucleoside diphosphate kinase complexed with TDP 2 Function 3 About this Structure 4 Reference

X-ray structure of Acanthamoeba ployphaga mimivirus nucleoside diphosphate kinase complexed with TDP

Template:ABSTRACT PUBMED 19439473

Function

[NDK_MIMIV] Plays a role in the synthesis of nucleoside triphosphates. This activity may optimize the replication of the AT-rich (73%) viral genome in a thymidine-limited host environment.

About this Structure

2b8q is a 6 chain structure with sequence from Mimivirus. Full crystallographic information is available from OCA.

Reference

• Jeudy S, Lartigue A, Claverie JM, Abergel C. Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase. J Virol. 2009 Jul;83(14):7142-50. Epub 2009 May 13. PMID:19439473 doi:10.1128/JVI.00511-09