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2dde
From Proteopedia
(Difference between revisions)
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| - | + | ==Structure of cinnamycin complexed with lysophosphatidylethanolamine== | |
| - | === | + | <StructureSection load='2dde' size='340' side='right' caption='[[2dde]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DDE FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aj1|1aj1]], [[1mqx|1mqx]], [[1mqy|1mqy]], [[1mqz|1mqz]], [[1qow|1qow]], [[1w9n|1w9n]], [[1wco|1wco]], [[2ktn|2ktn]], [[2kto|2kto]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The three-dimensional structure of a complex of cinnamycin, a 19-amino acid residue immunopotentiator peptide, and lysophosphatidylethanolamine was determined by 1H-NMR. The complex was cylindrical in shape, 11 A in diameter and 26 A in length, excluding the acyl chain of the phospholipid. The peptide had a hydrophobic pocket surrounded by residues Phe-7 through Ala(S)-14 to bind to the head group of the ligand. Fitting of the head group to the hydrophobic pocket was so good that other than a glycerophosphoethanolamine head group would be unable to fit the pocket. The goodness of the fitting is compatible with the strict specificity of ligand binding of the peptide. | ||
| - | + | Structure determination of an immunopotentiator peptide, cinnamycin, complexed with lysophosphatidylethanolamine by 1H-NMR1.,Hosoda K, Ohya M, Kohno T, Maeda T, Endo S, Wakamatsu K J Biochem. 1996 Feb;119(2):226-30. PMID:8882709<ref>PMID:8882709</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Streptomyces griseoverticillatus]] | [[Category: Streptomyces griseoverticillatus]] | ||
| - | [[Category: Endo, S | + | [[Category: Endo, S]] |
| - | [[Category: Hosoda, K | + | [[Category: Hosoda, K]] |
| - | [[Category: Kohno, T | + | [[Category: Kohno, T]] |
| - | [[Category: Maeda, T | + | [[Category: Maeda, T]] |
| - | [[Category: Ohya, M | + | [[Category: Ohya, M]] |
| - | [[Category: Wakamatsu, K | + | [[Category: Wakamatsu, K]] |
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
[[Category: Antimicrobial]] | [[Category: Antimicrobial]] | ||
Revision as of 08:33, 8 December 2014
Structure of cinnamycin complexed with lysophosphatidylethanolamine
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