1avu
From Proteopedia
(New page: 200px<br /> <applet load="1avu" size="450" color="white" frame="true" align="right" spinBox="true" caption="1avu, resolution 2.30Å" /> '''TRYPSIN INHIBITOR F...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1AVU is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AVU OCA]]. | + | 1AVU is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]]. Structure known Active Site: ACT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AVU OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: trypsin inhibitor]] | [[Category: trypsin inhibitor]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:43:36 2007'' |
Revision as of 06:38, 30 October 2007
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TRYPSIN INHIBITOR FROM SOYBEAN (STI)
Overview
The Kunitz-type trypsin inhibitor from soybean (STI) consists of 181 amino, acid residues with two disulfide bridges. Its crystal structures have been, determined in complex with porcine pancreatic trypsin in two crystal forms, (an orthorhombic form at 1.75 A resolution and a tetragonal form at 1.9 A), and in the free state at 2.3 A resolution. They have been refined to, crystallographic R-values of 18.9%, 21.6% and 19.8%, respectively. The, three models of STI reported here represent a significant improvement over, the partial inhibitor structure in the complex, which was previously, determined at a nominal resolution of 2.6 A by the multiple isomorphous, replacement method. This study provides the first high-resolution picture, of the complex between a Kunitz-type proteinase inhibitor ... [(full description)]
About this Structure
1AVU is a [Single protein] structure of sequence from [[1]]. Structure known Active Site: ACT. Full crystallographic information is available from [OCA].
Reference
Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator., Song HK, Suh SW, J Mol Biol. 1998 Jan 16;275(2):347-63. PMID:9466914
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