4l4r

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== Structural highlights ==
== Structural highlights ==
[[4l4r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4R OCA]. <br>
[[4l4r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4R OCA]. <br>
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<b>Related:</b> [[4l4s|4l4s]]<br>
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<b>[[Related_structure|Related:]]</b> [[4l4s|4l4s]]<br>
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
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<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l4r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l4r RCSB], [http://www.ebi.ac.uk/pdbsum/4l4r PDBsum]</span><br>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref>
[[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref>

Revision as of 09:57, 30 April 2014

Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme

4l4r, resolution 2.10Å

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