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4l4s

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<StructureSection load='4l4s' size='340' side='right' caption='[[4l4s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='4l4s' size='340' side='right' caption='[[4l4s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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[[4l4s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4S OCA]. <br>
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<table><tr><td colspan='2'>[[4l4s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4S OCA]. <br>
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<b>[[Ligand|Ligands:]]</b> <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene><br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene><br>
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<b>[[Related_structure|Related:]]</b> [[4l4r|4l4r]]<br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l4r|4l4r]]</td></tr>
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<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l4s RCSB], [http://www.ebi.ac.uk/pdbsum/4l4s PDBsum]</span><br>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l4s RCSB], [http://www.ebi.ac.uk/pdbsum/4l4s PDBsum]</span></td></tr>
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<table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref>
[[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref>

Revision as of 09:27, 1 May 2014

Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme

4l4s, resolution 2.90Å

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