4py0
From Proteopedia
(Difference between revisions)
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<StructureSection load='4py0' size='340' side='right' caption='[[4py0]], [[Resolution|resolution]] 3.10Å' scene=''> | <StructureSection load='4py0' size='340' side='right' caption='[[4py0]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | [[4py0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PY0 OCA]. <br> | + | <table><tr><td colspan='2'>[[4py0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PY0 OCA]. <br> |
| - | <b>[[Ligand|Ligands:]]</b> <scene name='pdbligand=6AT:2-(METHYLSULFANYL)ADENOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)'>6AT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene><br> | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AT:2-(METHYLSULFANYL)ADENOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)'>6AT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene><br> |
| - | <b>[[Related_structure|Related:]]</b> [[4ntj|4ntj]], [[4pxz|4pxz]]< | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ntj|4ntj]], [[4pxz|4pxz]]</td></tr> |
| - | <b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span>< | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr> |
| - | <b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4py0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4py0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4py0 RCSB], [http://www.ebi.ac.uk/pdbsum/4py0 PDBsum]</span>< | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4py0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4py0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4py0 RCSB], [http://www.ebi.ac.uk/pdbsum/4py0 PDBsum]</span></td></tr> |
| + | <table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/P2Y12_HUMAN P2Y12_HUMAN]] Resistance to clopidogrel in myocardial infarction, cerebrovascular accident, oblitering arteriopathy of the lower limbs;P2Y12 defect. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/P2Y12_HUMAN P2Y12_HUMAN]] Resistance to clopidogrel in myocardial infarction, cerebrovascular accident, oblitering arteriopathy of the lower limbs;P2Y12 defect. The disease is caused by mutations affecting the gene represented in this entry. | ||
Revision as of 09:31, 1 May 2014
Crystal structure of P2Y12 receptor in complex with 2MeSATP
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Categories: Cherezov, V. | GPCR, GPCR Network. | Gao, Z G. | Han, G W. | Jacobson, K A. | Jiang, H. | Katritch, V. | Li, T. | Ma, L. | Muller, C E. | Paoletta, S. | Stevens, R C. | Wu, B. | Yang, H. | Zhang, D. | Zhang, J. | Zhang, K. | Zhang, W. | Zhao, Q. | Gpcr | Gpcr network | Membrane | Membrane protein | Partial agonist-bound | Platelet activation | Psi-biology | Purinergic receptor p2y12 | Signaling membrane protein | Signaling protein-nucleotide complex | Structural genomic
