JMS/Sandbox21
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
| - | <scene name='58/583419/Pka_reg/1'> | + | <scene name='58/583419/Pka_reg/1'>The PKA catalytic unit (C) crystalized with the regulatory unit (R)</scene>, pdb structure [[3fhi]], is shown with small lobe in gray, large lobe in tan and regulatory unit in light blue. The residues from exon 1 <scene name='58/583419/Pka_reg/2'>are distant</scene> from the residues which bind to the regulatory unit R. The last three residues from exon 1 (residues # 13-15) are the only translated amino acids from first exon of pkaca that were well-crystalized in this structure. These three residues are <scene name='58/583419/Pka_reg/3'>distant from PKI-interacting residues</scene> - a second regulator/inhibitor of 'C', as well. This is also obvious from the pdb structure for the <scene name='58/583419/Pka_pki/1'>crystal of C bound to PKI</scene>, [[1atp]]. |
| - | <scene name='58/583419/Pka_reg/2'> | + | |
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</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 00:47, 1 May 2014
Your Heading Here (maybe something like 'Structure')
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
