1e9w

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<StructureSection load='1e9w' size='340' side='right' caption='[[1e9w]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
<StructureSection load='1e9w' size='340' side='right' caption='[[1e9w]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1e9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9W OCA]. <br>
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<table><tr><td colspan='2'>[[1e9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E9W FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BB9:(2Z)-2-AMINO-3-SULFANYLPROP-2-ENOIC+ACID'>BB9</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=MH6:3-HYDROXY-2-IMINOPROPANOIC+ACID'>MH6</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=QUA:8-HYDROXY-4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLIC+ACID'>QUA</scene>, <scene name='pdbligand=TS9:(2S,3S,4R)-2-AMINO-3,4-DIHYDROXY-3-METHYLPENTANOIC+ACID'>TS9</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BB9:(2Z)-2-AMINO-3-SULFANYLPROP-2-ENOIC+ACID'>BB9</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=MH6:3-HYDROXY-2-IMINOPROPANOIC+ACID'>MH6</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=QUA:8-HYDROXY-4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLIC+ACID'>QUA</scene>, <scene name='pdbligand=TS9:(2S,3S,4R)-2-AMINO-3,4-DIHYDROXY-3-METHYLPENTANOIC+ACID'>TS9</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1d8t|1d8t]], [[1oln|1oln]], [[2c77|2c77]], [[2jq7|2jq7]], [[2zjp|2zjp]], [[3cf5|3cf5]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1d8t|1d8t]], [[1oln|1oln]], [[2c77|2c77]], [[2jq7|2jq7]], [[2zjp|2zjp]], [[3cf5|3cf5]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e9w RCSB], [http://www.ebi.ac.uk/pdbsum/1e9w PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e9w RCSB], [http://www.ebi.ac.uk/pdbsum/1e9w PDBsum]</span></td></tr>
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</table>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structure of the macrocycle thiostrepton solved using the anomalous dispersion contribution of sulfur.,Bond CS, Shaw MP, Alphey MS, Hunter WN Acta Crystallogr D Biol Crystallogr. 2001 May;57(Pt 5):755-8. Epub 2001, Apr 24. PMID:11320328<ref>PMID:11320328</ref>
Structure of the macrocycle thiostrepton solved using the anomalous dispersion contribution of sulfur.,Bond CS, Shaw MP, Alphey MS, Hunter WN Acta Crystallogr D Biol Crystallogr. 2001 May;57(Pt 5):755-8. Epub 2001, Apr 24. PMID:11320328<ref>PMID:11320328</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Streptomyces azureus]]
[[Category: Streptomyces azureus]]
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[[Category: Alphey, M S.]]
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[[Category: Alphey, M S]]
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[[Category: Bond, C S.]]
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[[Category: Bond, C S]]
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[[Category: Hunter, W N.]]
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[[Category: Hunter, W N]]
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[[Category: Shaw, M P.]]
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[[Category: Shaw, M P]]
[[Category: Antibacterial]]
[[Category: Antibacterial]]
[[Category: Antibiotic]]
[[Category: Antibiotic]]

Revision as of 22:43, 22 December 2014

Structure of the macrocycle thiostrepton solved using the anomalous dispersive contribution from sulfur

1e9w, resolution 1.02Å

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