User:A. Rahim Zalal/Sandbox 1

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===Protein Primary Sequence===
===Protein Primary Sequence===
The sequence for histone H2A type 1 (human) is presented here<ref>PMID:12408966</ref>:
The sequence for histone H2A type 1 (human) is presented here<ref>PMID:12408966</ref>:
 +
 +
10 20 30 40 50 60
 +
MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT
 +
 +
70 80 90 100 110 120
 +
AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK
 +
 +
130
 +
TESHHKAKGK
===Coding DNA Sequence===
===Coding DNA Sequence===
 +
The coding DNA sequence for the H2A type 1 subunit (human)<ref>PMID:1916825</ref>:
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>ENA|AAA63191|AAA63191.1 Homo sapiens (human) histone H2A.1 : Location:1..393
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ATGTCTGGACGTGGAAAGCAAGGCGGCAAAGCTCGGGCAAAAGCTAAAACGCGTTCTTCC
 +
AGGGCCGGTCTTCAGTTTCCAGTTGGCCGTGTGCACCGCCTCCTCCGCAAAGGCAACTAC
 +
TCCGAACGAGTCGGGGCCGGCGCTCCAGTGTACCTGGCAGCGGTGCTGGAATATCTGACG
 +
GCCGAGATCTTAGAGCTAGCTGGCAACGCGGCTCGCGACAATAAGAAGACCCGCATCATC
 +
CCGCGCCACCTGCAGCTAGCCATCCGCAACGACGAGGAGCTAAATAAGCTTCTAGGTCGC
 +
GTGACCATCGCGCAGGGCGGTGTCCTGCCCAACATCCAGGCCGTATTGCTGCCTAAGAAG
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ACGGAGAGCCACCATAAGGCCAAGGGCAAGTGA
== Mechanism ==
== Mechanism ==

Revision as of 16:56, 2 May 2014

Histone (H2A)

Holder text

Contents


Structure

Histone Complexed with DNA to form Nucleosome

Drag the structure with the mouse to rotate

Function

Sequence

Protein Primary Sequence

The sequence for histone H2A type 1 (human) is presented here[3]: 

       10         20         30         40         50         60

MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT 

       70         80         90        100        110        120

AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK 

      130

TESHHKAKGK

Coding DNA Sequence

The coding DNA sequence for the H2A type 1 subunit (human)[4]: >ENA|AAA63191|AAA63191.1 Homo sapiens (human) histone H2A.1 : Location:1..393 ATGTCTGGACGTGGAAAGCAAGGCGGCAAAGCTCGGGCAAAAGCTAAAACGCGTTCTTCC AGGGCCGGTCTTCAGTTTCCAGTTGGCCGTGTGCACCGCCTCCTCCGCAAAGGCAACTAC TCCGAACGAGTCGGGGCCGGCGCTCCAGTGTACCTGGCAGCGGTGCTGGAATATCTGACG GCCGAGATCTTAGAGCTAGCTGGCAACGCGGCTCGCGACAATAAGAAGACCCGCATCATC CCGCGCCACCTGCAGCTAGCCATCCGCAACGACGAGGAGCTAAATAAGCTTCTAGGTCGC GTGACCATCGCGCAGGGCGGTGTCCTGCCCAACATCCAGGCCGTATTGCTGCCTAAGAAG ACGGAGAGCCACCATAAGGCCAAGGGCAAGTGA

Mechanism

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. ↑ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ. The human and mouse replication-dependent histone genes. Genomics. 2002 Nov;80(5):487-98. PMID:12408966
  4. ↑ Albig W, Kardalinou E, Drabent B, Zimmer A, Doenecke D. Isolation and characterization of two human H1 histone genes within clusters of core histone genes. Genomics. 1991 Aug;10(4):940-8. PMID:1916825

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A. Rahim Zalal

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