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4m90

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<StructureSection load='4m90' size='340' side='right' caption='[[4m90]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4m90' size='340' side='right' caption='[[4m90]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4m90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M90 OCA]. <br>
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<table><tr><td colspan='2'>[[4m90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M90 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4m8g|4m8g]], [[4m91|4m91]], [[4m92|4m92]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4m8g|4m8g]], [[4m91|4m91]], [[4m92|4m92]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TUSC3, N33 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TUSC3, N33 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m90 RCSB], [http://www.ebi.ac.uk/pdbsum/4m90 PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m90 RCSB], [http://www.ebi.ac.uk/pdbsum/4m90 PDBsum]</span></td></tr>
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</table>
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<table>
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== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/TUSC3_HUMAN TUSC3_HUMAN]] Autosomal recessive nonsyndromic intellectual deficit. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/TUSC3_HUMAN TUSC3_HUMAN]] Autosomal recessive nonsyndromic intellectual deficit. The disease is caused by mutations affecting the gene represented in this entry.
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Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.,Mohorko E, Owen RL, Malojcic G, Brozzo MS, Aebi M, Glockshuber R Structure. 2014 Apr 8;22(4):590-601. doi: 10.1016/j.str.2014.02.013. Epub 2014, Mar 27. PMID:24685145<ref>PMID:24685145</ref>
Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.,Mohorko E, Owen RL, Malojcic G, Brozzo MS, Aebi M, Glockshuber R Structure. 2014 Apr 8;22(4):590-601. doi: 10.1016/j.str.2014.02.013. Epub 2014, Mar 27. PMID:24685145<ref>PMID:24685145</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Aebi, M.]]
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[[Category: Aebi, M]]
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[[Category: Brozzo, M S.]]
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[[Category: Brozzo, M S]]
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[[Category: Glockshuber, R.]]
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[[Category: Glockshuber, R]]
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[[Category: Malojcic, G.]]
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[[Category: Malojcic, G]]
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[[Category: Mohorko, E.]]
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[[Category: Mohorko, E]]
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[[Category: Owen, R L.]]
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[[Category: Owen, R L]]
[[Category: Endoplasmic reticulum]]
[[Category: Endoplasmic reticulum]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Redox active]]
[[Category: Redox active]]
[[Category: Thioredoxin-like fold]]
[[Category: Thioredoxin-like fold]]

Revision as of 08:52, 5 January 2015

crystal structure of oxidized hN33/Tusc3

4m90, resolution 1.60Å

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