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4ch3
From Proteopedia
(Difference between revisions)
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<StructureSection load='4ch3' size='340' side='right' caption='[[4ch3]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='4ch3' size='340' side='right' caption='[[4ch3]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ch3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Metma Metma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CH3 OCA]. <br> | + | <table><tr><td colspan='2'>[[4ch3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Metma Metma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CH3 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YLB:5-O-({[(2R)-2-AMINO-6-(BUTANOYLAMINO)HEXANOYL]OXY}PHOSPHINATO)ADENOSINE'>YLB</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YLB:5-O-({[(2R)-2-AMINO-6-(BUTANOYLAMINO)HEXANOYL]OXY}PHOSPHINATO)ADENOSINE'>YLB</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ch4|4ch4]], [[4ch5|4ch5]], [[4ch6|4ch6]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ch4|4ch4]], [[4ch5|4ch5]], [[4ch6|4ch6]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrrolysine--tRNA(Pyl)_ligase Pyrrolysine--tRNA(Pyl) ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.26 6.1.1.26] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ch3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ch3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ch3 RCSB], [http://www.ebi.ac.uk/pdbsum/4ch3 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ch3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ch3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ch3 RCSB], [http://www.ebi.ac.uk/pdbsum/4ch3 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA]] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structural basis for the site-specific incorporation of lysine derivatives into proteins.,Flugel V, Vrabel M, Schneider S PLoS One. 2014 Apr 23;9(4):e96198. doi: 10.1371/journal.pone.0096198. eCollection, 2014. PMID:24760130<ref>PMID:24760130</ref> | Structural basis for the site-specific incorporation of lysine derivatives into proteins.,Flugel V, Vrabel M, Schneider S PLoS One. 2014 Apr 23;9(4):e96198. doi: 10.1371/journal.pone.0096198. eCollection, 2014. PMID:24760130<ref>PMID:24760130</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Metma]] | [[Category: Metma]] | ||
| - | [[Category: Fluegel, V | + | [[Category: Fluegel, V]] |
| - | [[Category: Schneider, S | + | [[Category: Schneider, S]] |
| - | [[Category: Vrabel, M | + | [[Category: Vrabel, M]] |
[[Category: Ligase]] | [[Category: Ligase]] | ||
[[Category: Non-natural amino acid]] | [[Category: Non-natural amino acid]] | ||
[[Category: Pyrrolysine]] | [[Category: Pyrrolysine]] | ||
Revision as of 18:28, 25 December 2014
Structure of pyrrolysyl-tRNA synthetase in complex with adenylated butyryl lysine
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