4gsn

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<StructureSection load='4gsn' size='340' side='right' caption='[[4gsn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4gsn' size='340' side='right' caption='[[4gsn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gsn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anoga Anoga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSN OCA]. <br>
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<table><tr><td colspan='2'>[[4gsn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anoga Anoga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GSN FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2il3|2il3]], [[2imi|2imi]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2il3|2il3]], [[2imi|2imi]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gsn RCSB], [http://www.ebi.ac.uk/pdbsum/4gsn PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gsn RCSB], [http://www.ebi.ac.uk/pdbsum/4gsn PDBsum]</span></td></tr>
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</table>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Metabolic and Target-Site Mechanisms Combine to Confer Strong DDT Resistance in Anopheles gambiae.,Mitchell SN, Rigden DJ, Dowd AJ, Lu F, Wilding CS, Weetman D, Dadzie S, Jenkins AM, Regna K, Boko P, Djogbenou L, Muskavitch MA, Ranson H, Paine MJ, Mayans O, Donnelly MJ PLoS One. 2014 Mar 27;9(3):e92662. doi: 10.1371/journal.pone.0092662. eCollection, 2014. PMID:24675797<ref>PMID:24675797</ref>
Metabolic and Target-Site Mechanisms Combine to Confer Strong DDT Resistance in Anopheles gambiae.,Mitchell SN, Rigden DJ, Dowd AJ, Lu F, Wilding CS, Weetman D, Dadzie S, Jenkins AM, Regna K, Boko P, Djogbenou L, Muskavitch MA, Ranson H, Paine MJ, Mayans O, Donnelly MJ PLoS One. 2014 Mar 27;9(3):e92662. doi: 10.1371/journal.pone.0092662. eCollection, 2014. PMID:24675797<ref>PMID:24675797</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Anoga]]
[[Category: Anoga]]
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[[Category: Lu, F.]]
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[[Category: Lu, F]]
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[[Category: Mayans, O.]]
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[[Category: Mayans, O]]
[[Category: Gst]]
[[Category: Gst]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 13:38, 4 January 2015

Crystal Structure of GSTe2 ZAN/U variant from Anopheles gambiae

4gsn, resolution 2.30Å

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