4q0o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 2: Line 2:
<StructureSection load='4q0o' size='340' side='right' caption='[[4q0o]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
<StructureSection load='4q0o' size='340' side='right' caption='[[4q0o]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4q0o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q0O OCA]. <br>
+
<table><tr><td colspan='2'>[[4q0o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q0O FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2XC:(2E)-1-(2-HYDROXYPHENYL)-3-[(3R)-3-PHENYLPIPERIDIN-1-YL]PROP-2-EN-1-ONE'>2XC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene><br>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2XC:(2E)-1-(2-HYDROXYPHENYL)-3-[(3R)-3-PHENYLPIPERIDIN-1-YL]PROP-2-EN-1-ONE'>2XC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q0n|4q0n]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q0n|4q0n]]</td></tr>
-
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q0o RCSB], [http://www.ebi.ac.uk/pdbsum/4q0o PDBsum]</span></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q0o RCSB], [http://www.ebi.ac.uk/pdbsum/4q0o PDBsum]</span></td></tr>
+
</table>
-
<table>
+
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/PB1_HUMAN PB1_HUMAN]] Defects in PBRM1 are a cause of renal cell carcinoma (RCC) [MIM:[http://omim.org/entry/144700 144700]]. It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma.<ref>PMID:21248752</ref>
[[http://www.uniprot.org/uniprot/PB1_HUMAN PB1_HUMAN]] Defects in PBRM1 are a cause of renal cell carcinoma (RCC) [MIM:[http://omim.org/entry/144700 144700]]. It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma.<ref>PMID:21248752</ref>
Line 16: Line 15:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith, C H]]
-
[[Category: Bountra, C.]]
+
[[Category: Bountra, C]]
-
[[Category: Delft, F von.]]
+
[[Category: Delft, F von]]
-
[[Category: Edwards, A M.]]
+
[[Category: Edwards, A M]]
-
[[Category: Filippakopoulos, P.]]
+
[[Category: Filippakopoulos, P]]
-
[[Category: Knapp, S.]]
+
[[Category: Knapp, S]]
-
[[Category: Picaud, S.]]
+
[[Category: Picaud, S]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Structural genomic]]
[[Category: Baf180]]
[[Category: Baf180]]
[[Category: Brg1-associated factor 180]]
[[Category: Brg1-associated factor 180]]
Line 35: Line 34:
[[Category: Polybromo-1d]]
[[Category: Polybromo-1d]]
[[Category: Sgc]]
[[Category: Sgc]]
-
[[Category: Structural genomics consortium]]
 
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]

Revision as of 09:02, 5 January 2015

Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand

4q0o, resolution 1.83Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4q0o"
Personal tools