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2rrm
From Proteopedia
(Difference between revisions)
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<StructureSection load='2rrm' size='340' side='right' caption='[[2rrm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2rrm' size='340' side='right' caption='[[2rrm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2rrm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RRM OCA]. | + | <table><tr><td colspan='2'>[[2rrm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RRM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RRM FirstGlance]. <br> |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rrm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rrm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rrm RCSB], [http://www.ebi.ac.uk/pdbsum/2rrm PDBsum]</span></td></tr> | |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rrm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rrm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rrm RCSB], [http://www.ebi.ac.uk/pdbsum/2rrm PDBsum]</span></td></tr> | + | </table> |
| - | <table> | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/ZO1_MOUSE ZO1_MOUSE]] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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(1)H, (13)C, and (15)N resonance assignment of the first PDZ domain of mouse ZO-1.,Umetsu Y, Goda N, Taniguchi R, Satomura K, Ikegami T, Furuse M, Hiroaki H Biomol NMR Assign. 2011 Mar 24. PMID:21431884<ref>PMID:21431884</ref> | (1)H, (13)C, and (15)N resonance assignment of the first PDZ domain of mouse ZO-1.,Umetsu Y, Goda N, Taniguchi R, Satomura K, Ikegami T, Furuse M, Hiroaki H Biomol NMR Assign. 2011 Mar 24. PMID:21431884<ref>PMID:21431884</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Furuse, M | + | [[Category: Furuse, M]] |
| - | [[Category: Goda, N | + | [[Category: Goda, N]] |
| - | [[Category: Hiroaki, H | + | [[Category: Hiroaki, H]] |
| - | [[Category: Ikegami, T | + | [[Category: Ikegami, T]] |
| - | [[Category: Satomura, K | + | [[Category: Satomura, K]] |
| - | [[Category: Taniguchi, R | + | [[Category: Taniguchi, R]] |
| - | [[Category: Umetsu, Y | + | [[Category: Umetsu, Y]] |
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Intercellular adhesion]] | [[Category: Intercellular adhesion]] | ||
Revision as of 06:14, 25 December 2014
Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1
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