User:Jaakko Itkonen
From Proteopedia
(Difference between revisions)
| Line 10: | Line 10: | ||
*[[User:Jaakko Itkonen/Sandbox CNTF]] | *[[User:Jaakko Itkonen/Sandbox CNTF]] | ||
| + | |||
| + | ==Introduction== | ||
Ciliary neutrophic factor (CNTF) is a nerve growth factor belonging to the IL-6 family | Ciliary neutrophic factor (CNTF) is a nerve growth factor belonging to the IL-6 family | ||
Revision as of 10:53, 7 May 2014
- Full Real Name: Jaakko Matias Itkonen
- Position: Student
- Institution (NO ABBREVIATIONS): University of Helsinki, Faculty Of Pharmacy, Division of Pharmaceutical Biosciences
- City, State/Province, Country: Helsinki, Finland
- Field of Expertise or Study: Pharmacy
Introduction
Ciliary neutrophic factor (CNTF) is a nerve growth factor belonging to the IL-6 family of neuropoietic cytokines. Other members of this family include leukaemie inhibitory factor (LIF), IL-6, IL-11 and oncostatin M (Wang 2012). CNTF is a roughly 22 kDa protein consisting of a single peptide chain of 200 amino acid residues, and like many other cytokines, is folded into a four α-helix bundle.
Fig. 1 X-ray structure of a truncated form of hCNTF (2-187)
