4bws
From Proteopedia
(Difference between revisions)
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<StructureSection load='4bws' size='340' side='right' caption='[[4bws]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4bws' size='340' side='right' caption='[[4bws]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bws]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BWS OCA]. <br> | + | <table><tr><td colspan='2'>[[4bws]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BWS FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bwq|4bwq]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bwq|4bwq]]</td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bws OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bws RCSB], [http://www.ebi.ac.uk/pdbsum/4bws PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/PQBP1_HUMAN PQBP1_HUMAN]] X-linked intellectual deficit, Sutherland-Haan type;X-linked intellectual deficit, Golabi-Ito-Hall type;X-linked intellectual deficit, Porteous type;Hamel cerebro-palato-cardiac syndrome. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/PQBP1_HUMAN PQBP1_HUMAN]] X-linked intellectual deficit, Sutherland-Haan type;X-linked intellectual deficit, Golabi-Ito-Hall type;X-linked intellectual deficit, Porteous type;Hamel cerebro-palato-cardiac syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
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Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15kD.,Mizuguchi M, Obita T, Serita T, Kojima R, Nabeshima Y, Okazawa H Nat Commun. 2014 Apr 30;5:3822. doi: 10.1038/ncomms4822. PMID:24781215<ref>PMID:24781215</ref> | Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15kD.,Mizuguchi M, Obita T, Serita T, Kojima R, Nabeshima Y, Okazawa H Nat Commun. 2014 Apr 30;5:3822. doi: 10.1038/ncomms4822. PMID:24781215<ref>PMID:24781215</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| - | [[Category: Kojima, R | + | [[Category: Kojima, R]] |
| - | [[Category: Mizuguchi, M | + | [[Category: Mizuguchi, M]] |
| - | [[Category: Morimoto, T | + | [[Category: Morimoto, T]] |
| - | [[Category: Nabeshima, Y | + | [[Category: Nabeshima, Y]] |
| - | [[Category: Obita, T | + | [[Category: Obita, T]] |
| - | [[Category: Okazawa, H | + | [[Category: Okazawa, H]] |
| - | [[Category: Serita, T | + | [[Category: Serita, T]] |
[[Category: Neurodegenerative disorder]] | [[Category: Neurodegenerative disorder]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 12:50, 4 January 2015
Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD.
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