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4l8y

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<StructureSection load='4l8y' size='340' side='right' caption='[[4l8y]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
<StructureSection load='4l8y' size='340' side='right' caption='[[4l8y]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4l8y]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L8Y OCA]. <br>
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<table><tr><td colspan='2'>[[4l8y]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L8Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L8Y FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l7q|4l7q]], [[4l8f|4l8f]], [[4l8w|4l8w]], [[4l95|4l95]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l7q|4l7q]], [[4l8f|4l8f]], [[4l8w|4l8w]], [[4l95|4l95]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyl_hydrolase Gamma-glutamyl hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.9 3.4.19.9] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l8y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l8y RCSB], [http://www.ebi.ac.uk/pdbsum/4l8y PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l8y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l8y RCSB], [http://www.ebi.ac.uk/pdbsum/4l8y PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase.,Chuankhayan P, Kao TT, Lin CC, Guan HH, Nakagawa A, Fu TF, Chen CJ J Med Chem. 2013 Oct 10;56(19):7625-35. doi: 10.1021/jm401013e. Epub 2013 Sep 27. PMID:24028568<ref>PMID:24028568</ref>
Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase.,Chuankhayan P, Kao TT, Lin CC, Guan HH, Nakagawa A, Fu TF, Chen CJ J Med Chem. 2013 Oct 10;56(19):7625-35. doi: 10.1021/jm401013e. Epub 2013 Sep 27. PMID:24028568<ref>PMID:24028568</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Gamma-glutamyl hydrolase]]
[[Category: Gamma-glutamyl hydrolase]]
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[[Category: Chen, C J.]]
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[[Category: Chen, C J]]
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[[Category: Chuankhayan, P.]]
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[[Category: Chuankhayan, P]]
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[[Category: Fu, T F.]]
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[[Category: Fu, T F]]
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[[Category: Kao, T T.]]
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[[Category: Kao, T T]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Sandwiched-like domain]]
[[Category: Sandwiched-like domain]]

Revision as of 09:34, 5 January 2015

Crystal structure of gamma-glutamyl hydrolase (C108A) from zebrafish

4l8y, resolution 1.97Å

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