4cy1
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
<StructureSection load='4cy1' size='340' side='right' caption='[[4cy1]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='4cy1' size='340' side='right' caption='[[4cy1]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4cy1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CY1 OCA]. <br> | + | <table><tr><td colspan='2'>[[4cy1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CY1 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cy2|4cy2]], [[4cy3|4cy3]], [[4cy5|4cy5]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cy2|4cy2]], [[4cy3|4cy3]], [[4cy5|4cy5]]</td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cy1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cy1 RCSB], [http://www.ebi.ac.uk/pdbsum/4cy1 PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/KANL1_HUMAN KANL1_HUMAN]] 17q21.31 microdeletion syndrome;Koolen-De Vries syndrome due to a point mutation. | [[http://www.uniprot.org/uniprot/KANL1_HUMAN KANL1_HUMAN]] 17q21.31 microdeletion syndrome;Koolen-De Vries syndrome due to a point mutation. | ||
| Line 18: | Line 17: | ||
Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex.,Dias J, Van Nguyen N, Georgiev P, Gaub A, Brettschneider J, Cusack S, Kadlec J, Akhtar A Genes Dev. 2014 May 1;28(9):929-42. doi: 10.1101/gad.240200.114. PMID:24788516<ref>PMID:24788516</ref> | Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex.,Dias J, Van Nguyen N, Georgiev P, Gaub A, Brettschneider J, Cusack S, Kadlec J, Akhtar A Genes Dev. 2014 May 1;28(9):929-42. doi: 10.1101/gad.240200.114. PMID:24788516<ref>PMID:24788516</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
| Line 24: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Brettschneider, J | + | [[Category: Brettschneider, J]] |
| - | [[Category: Cusack, S | + | [[Category: Cusack, S]] |
| - | [[Category: Dias, J | + | [[Category: Dias, J]] |
| - | [[Category: Kadlec, J | + | [[Category: Kadlec, J]] |
[[Category: Chromatin]] | [[Category: Chromatin]] | ||
[[Category: Epigenetic regulator]] | [[Category: Epigenetic regulator]] | ||
[[Category: Histone acetylation]] | [[Category: Histone acetylation]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 13:50, 4 January 2015
Crystal structure of the KANSL1-WDR5 complex.
| |||||||||||
