4cy2
From Proteopedia
(Difference between revisions)
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<StructureSection load='4cy2' size='340' side='right' caption='[[4cy2]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4cy2' size='340' side='right' caption='[[4cy2]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4cy2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CY2 OCA]. <br> | + | <table><tr><td colspan='2'>[[4cy2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CY2 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cy1|4cy1]], [[4cy3|4cy3]], [[4cy5|4cy5]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cy1|4cy1]], [[4cy3|4cy3]], [[4cy5|4cy5]]</td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cy2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cy2 RCSB], [http://www.ebi.ac.uk/pdbsum/4cy2 PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/KANL1_HUMAN KANL1_HUMAN]] 17q21.31 microdeletion syndrome;Koolen-De Vries syndrome due to a point mutation. | [[http://www.uniprot.org/uniprot/KANL1_HUMAN KANL1_HUMAN]] 17q21.31 microdeletion syndrome;Koolen-De Vries syndrome due to a point mutation. | ||
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Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex.,Dias J, Van Nguyen N, Georgiev P, Gaub A, Brettschneider J, Cusack S, Kadlec J, Akhtar A Genes Dev. 2014 May 1;28(9):929-42. doi: 10.1101/gad.240200.114. PMID:24788516<ref>PMID:24788516</ref> | Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex.,Dias J, Van Nguyen N, Georgiev P, Gaub A, Brettschneider J, Cusack S, Kadlec J, Akhtar A Genes Dev. 2014 May 1;28(9):929-42. doi: 10.1101/gad.240200.114. PMID:24788516<ref>PMID:24788516</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Brettschneider, J | + | [[Category: Brettschneider, J]] |
| - | [[Category: Cusack, S | + | [[Category: Cusack, S]] |
| - | [[Category: Dias, J | + | [[Category: Dias, J]] |
| - | [[Category: Kadlec, J | + | [[Category: Kadlec, J]] |
[[Category: Chromatin]] | [[Category: Chromatin]] | ||
[[Category: Epigenetic regulator]] | [[Category: Epigenetic regulator]] | ||
[[Category: Histone acetylation]] | [[Category: Histone acetylation]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 14:23, 4 January 2015
Crystal structure of the KANSL1-WDR5-KANSL2 complex.
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